Thermo Fisher Scientific CCR6 Polyclonal Antibody, Biotin
CCR6 단백질을 표적으로 하는 Biotin 결합 Rabbit Polyclonal Antibody. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. Human 및 Mouse 반응성. 고순도 Affinity chromatography 정제, 안정적인 보관용 glycerol buffer 포함.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–100 of human CCR6 protein (UniProt ID: P51684-1) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol and 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CCR6 is a member of the beta chemokine receptor family, predicted to be a seven-transmembrane G protein-coupled receptor. It is preferentially expressed by immature dendritic cells and memory T cells. Its ligand, macrophage inflammatory protein 3 alpha (MIP-3α), plays a role in B-lineage maturation and antigen-driven B-cell differentiation. CCR6 may regulate migration and recruitment of dendritic and T cells during inflammatory and immune responses. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: CCR6-612-BIOTIN_CCR6_P51684-1_Rabbit.svg, CCR6-612-BIOTIN_CCR6_P51684-1_Rabbit_PDP.jpeg)
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