Thermo Fisher Scientific ATF1 Polyclonal Antibody
ATF1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 최적화되어 있습니다. Human에서 반응하며, Rabbit IgG로 생산되었습니다. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 보관 권장됩니다.
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Applications
Tested Applications and Dilutions
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 208–271 of ATF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544568 |
Product Specific Information
- Recommended positive controls: HeLa, Jurkat, NT2D
- Predicted reactivity: Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates downstream target genes involved in growth, survival, and other cellular processes. The protein is phosphorylated at serine 63 by several kinases, enhancing its transcriptional activity and cell transformation potential. Gene fusions with FUS (chromosome 16) or EWSR1 (chromosome 22) are associated with angiomatoid fibrous histiocytoma and clear cell sarcoma. A pseudogene exists on chromosome 6.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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