Thermo Fisher Scientific IL-5 Chimeric Recombinant Rabbit Monoclonal Antibody (2E3)
Thermo Fisher의 IL-5 키메릭 재조합 토끼 단클론 항체(2E3)는 인간 IL-5에 특이적이며, Flow Cytometry, ELISA, Neutralization에 사용 가능합니다. 비결합형 액상 항체로, Protein A로 정제되었으며 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry (Flow) | 1:100 | - |
| ELISA | Assay-dependent | - |
| Neutralization (Neu) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2E3 |
| Immunogen | This antibody was raised by immunising CAF1 mice with human recombinant IL-5. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074620 |
Product Specific Information
Specificity: This antibody is specific for human rIL-5, and does not cross-react with human rIL-1alpha, rIL-1beta, rIL-4, rIL-8, rM-CSF, or rTGF-alpha.
Target Information
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. It is a main regulator of eosinopoiesis, eosinophil maturation, and activation. Elevated IL-5 production is associated with asthma and hypereosinophilic syndromes. The IL-5 receptor is a heterodimer, whose beta subunit is shared with receptors for IL-3 and CSF2 (GM-CSF). IL-5, along with IL-4, IL-13, and CSF2, forms a cytokine gene cluster on chromosome 5, and these cytokines are coordinately regulated by long-range elements on chromosome 5q31.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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