
Thermo Fisher Scientific CD1c Monoclonal Antibody (2A7C11)
CD1c 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, Flow cytometry, ELISA 등 다양한 응용에 적합합니다. 단백질 G로 정제된 액상 형태이며, 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A7C11 |
| Immunogen | Purified recombinant fragment of human CD1C (AA: extra 18–302) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091267 |
Target Information
The CD1C gene encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to major histocompatibility complex (MHC) proteins. These proteins form heterodimers with beta-2-microglobulin and mediate the presentation of lipid and glycolipid antigens to T cells. The human genome contains five CD1 family genes on chromosome 1, each differing in localization and lipid ligand specificity. CD1C localizes to late endosomes and lysosomes via a tyrosine-based motif and requires vesicular acidification for lipid antigen binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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