Thermo Fisher Scientific CD3d Monoclonal Antibody (6B6B12)
CD3d 단백질을 표적하는 마우스 단클론 항체로 인간 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry, ELISA 등 다양한 응용에 적합합니다. Protein G 정제, PBS 저장, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6B6B12 |
| Immunogen | Purified recombinant fragment of human CD3D (AA: 127–171) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090735 |
Target Information
CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and plays a critical role in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, which, together with other CD3 subunits, binds TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on T-cell surfaces.
Defects in the CD3d gene can cause severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been identified, though additional variants may exist with undefined full-length transcripts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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