Thermo Fisher Scientific CD1c Monoclonal Antibody (3G1B3)
CD1c 단백질을 표적으로 하는 Mouse IgG2b 단클론 항체로, Western blot, IHC, Flow cytometry, ELISA에 사용 가능. 인간 시료 반응성. Protein G 정제, PBS buffer 및 sodium azide 포함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:2000 | — |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | — |
| Flow Cytometry (Flow) | 1:200–1:400 | — |
| ELISA | 1:10,000 | — |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G1B3 |
| Immunogen | Purified recombinant fragment of human CD1c (AA: extra 18–302) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090998 |
Target Information
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin.
CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells.
The human genome contains five CD1 family genes organized in a cluster on chromosome 1.
CD1 family members differ in cellular localization and specificity for particular lipid ligands.
The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail and requires vesicular acidification to bind lipid antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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