Thermo Fisher Scientific PHYHD1 Monoclonal Antibody (OTI1A6), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

PHYHD1 (phytanoyl-CoA dioxygenase domain containing 1) is a 291 amino acid protein belonging to the PHYH family and PHYHD1 subfamily.
Encoded by a gene located on human chromosome 9q34.11, PHYHD1 exists as three alternatively spliced isoforms and likely functions as an α-ketoglutarate-dependent dioxygenase.
It participates in metal ion binding and oxidoreductase activity, incorporating two atoms of oxygen.
PHYHD1 is related to PHYH (phytanoyl-CoA 2-hydroxylase), an Fe(II) and 2-oxoglutarate (2OG)-dependent oxygenase involved in the α-oxidation of phytanic acid in peroxisomes.
Additionally, PHYHD1 may play a role in DNA methylation during early postnatal liver development and mammalian differentiation.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.