Thermo Fisher Scientific ACP1 Monoclonal Antibody (2A15)
Thermo Fisher Scientific의 ACP1 Monoclonal Antibody (2A15)은 인간 ACP1 단백질을 인식하는 Mouse IgG2a 단일클론 항체입니다. Western Blot 및 ELISA에 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 안정적인 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A15 |
| Immunogen | ACP1 (AAH07422, 1–158 a.a) full-length recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MAEQATKSVL FVCLGNICRS PIAEAVFRKL VTDQNISENW VIDSGAVSDW NVGRSPDPRA VSCLRNHGIH TAHKARQITK EDFATFDYIL CMDESNLRDL NRKSNQVKTC KAKIELLGSY DPQKQLIIED PYYGNDSDFE TVYQQCVRCC RAFLEKAH
Target Information
Low molecular weight protein tyrosine phosphatases, including the human red cell phosphatase HCPTP, are widely expressed cytosolic proteins (~18 kDa) that exist in distinct isoforms and are highly selective for phosphotyrosine.
HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase.
Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate and has a catalytic mechanism involving formation of a cystinylphosphate intermediate.
The crystal structure of the bovine heart-derived enzyme BHPTP shows a four-stranded central parallel β-sheet with flanking α-helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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