Thermo Fisher Scientific ACP1 Monoclonal Antibody (4B10)
Thermo Fisher Scientific의 ACP1 단클론 항체(4B10)는 Human, Mouse, Rat 시료에 반응하며 WB 및 ELISA에 적합합니다. GST 태그 결합 재조합 단백질을 면역원으로 사용하였으며, 액상 형태로 제공되고 -20°C에서 보관합니다. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B10 |
| Immunogen | ACP1 (AAH07422, 1–158 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MAEQATKSVL FVCLGNICRS PIAEAVFRKL VTDQNISENW VIDSGAVSDW NVGRSPDPRA VSCLRNHGIH TAHKARQITK EDFATFDYIL CMDESNLRDL NRKSNQVKTC KAKIELLGSY DPQKQLIIED PYYGNDSDFE TVYQQCVRCC RAFLEKAH
Target Information
Low molecular weight protein tyrosine phosphatases, including the human red cell phosphatase (HCPTP), are widely expressed cytosolic proteins (~18 kDa) existing in distinct isoforms. They show high selectivity for phosphotyrosine over phosphoserine or phosphothreonine.
HCPTP-A and HCPTP-B, expressed in human red cells and placenta, represent fast and slow forms of red cell acid phosphatase. Like other tyrosine phosphatases, HCPTP is inhibited by vanadate and operates via formation of a cystinylphosphate intermediate.
The crystal structure of the bovine heart enzyme (BHPTP) reveals a four-stranded central parallel β-sheet with flanking α-helices and an active-site cysteine residue in the conserved CXXXXXR motif.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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