Thermo Fisher Scientific ERBB2 Monoclonal Antibody (UMAB35), UltraMAB
ERBB2 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, ChIP 등 다양한 실험에 사용 가능. Human 및 Dog 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| ChIP assay (ChIP) | Assay-Dependent | - |
| Peptide Array (Array) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB35 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 676–1255 of human ERBB2 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ErbB2 (HER2) is a receptor tyrosine kinase overexpressed in certain breast tumors. Herceptin, a therapeutic monoclonal antibody, targets this kinase in the treatment of metastatic HER2-positive cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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