Thermo Fisher Scientific PADI4 Monoclonal Antibody (OTI6A2), TrueMAB
인간 PADI4 단백질을 인식하는 마우스 모노클로날 항체로 다양한 응용(WB, IHC, ICC/IF, Flow)에 적합. 고순도 액상 형태로 제공되며, -20°C에서 안정적으로 보관 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 299–588 of human PADI4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Catalyzes the citrullination/deimination of arginine residues of proteins.
Citrullinates histone H3 at Arg-8 and/or Arg-17 and histone H4 at Arg-3, preventing methylation by CARM1 and HRMT1L2/PRMT1, leading to transcriptional repression.
Also citrullinates EP300/P300 at Arg-2142, favoring its interaction with NCOA2/GRIP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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