Thermo Fisher Scientific NME4 Monoclonal Antibody (OTI1C11), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

NME4 is a protein kinase that transfers phosphate groups from donors like ATP to acceptor amino acids in substrate proteins. This fundamental mechanism mediates most signal transduction pathways in eukaryotic cells, regulating metabolism, transcription, cell cycle progression, cytoskeletal dynamics, apoptosis, and differentiation.
The protein kinase family includes over 500 gene products and is classified into 8 major groups based on catalytic domain sequences (tyrosine or serine/threonine kinases).
The AGC kinase group includes 63 kinases, such as the cyclic nucleotide-regulated protein kinase (PKA/PKG) family, protein kinase C (PKC) family, RAC/Akt family, ARK family (G protein-coupled receptor kinases), and RSK family (ribosomal protein S6 kinases).

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.