Thermo Fisher Scientific SNAP23 Recombinant Rabbit Monoclonal Antibody (2D8)
Recombinant rabbit monoclonal antibody recognizing human SNAP23. Suitable for IHC and ELISA applications. High purity via affinity chromatography. Provided in liquid form with PBS/glycerol buffer. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2D8 |
| Immunogen | A synthesized peptide derived from human SNAP23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092754 |
Target Information
Specificity of vesicular transport is regulated by interactions between vesicle-associated membrane proteins (synaptobrevin/VAMP) and target membrane proteins (syntaxin). Together with SNAP25, these form a complex serving as a binding site for membrane fusion machinery.
SNAP23, a homolog of SNAP25, is ubiquitously expressed and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high-affinity receptor for membrane fusion and regulates vesicle docking and fusion.
Two alternative transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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