Thermo Fisher Scientific NUP153 Polyclonal Antibody
NUP153 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot과 Immunocytochemistry에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 인간 시료에 반응. 핵공복합체 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human Nup153. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.23 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901988 |
Product Specific Information
- Centrifuge briefly prior to opening.
Target Information
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family.
Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm.
The protein encoded by this gene has three distinct domains:
- N-terminal region containing a pore targeting and an RNA-binding domain
- Central region containing multiple zinc finger motifs
- C-terminal region containing multiple XFXFG repeats
Alternative splicing results in multiple transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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