Thermo Fisher Scientific Human Dectin 1 Synthetic Peptide
Human CLEC7A(Dectin-1) 중심부 17 아미노산 서열 기반 합성 펩타이드. PA5-34382 항체의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태, PBS(pH 7.2) + 0.1% BSA, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP1425
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 17 amino acid sequence near the center of human CLEC7A.
PEP-1425 can be used as a blocking peptide with polyclonal antibody PA5-34382.
Target Information
CLEC7A (Dectin-1) is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells.
It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain and a cytoplasmic domain containing an ITAM motif.
CLEC7A functions as a pattern-recognition receptor recognizing beta-1,3- and beta-1,6-linked glucans from fungi and plants, playing a key role in innate immune responses.
Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering reactive oxygen species formation and oxidative burst.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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