Thermo Fisher Scientific Human NBS1 Synthetic Peptide
휴먼 NBS1 단백질의 카복시 말단 부위 15 아미노산 서열 기반 합성 펩타이드. 항체 차단(blocking) 실험용으로 사용 가능. 순도 높은 정제 상태로 제공되며 PBS(pH 7.2) 내 0.1% BSA 포함. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP1427
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 15 amino acid sequence near the carboxy terminus of human NIBRIN.
PEP-1427 can be used as a blocking peptide with polyclonal antibody PA5-34384.
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder associated with increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity. These findings reveal a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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