Thermo Fisher Scientific PAX8 Polyclonal Antibody
PAX8 단백질을 인식하는 염소 유래 polyclonal 항체로, Western blot 및 IHC(파라핀 절편) 실험에 적합합니다. 인간에 반응하며, 마우스 및 랫과의 교차 반응이 예측됩니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- PA518069
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PHNSIRSGHGGLN) corresponding to the N-terminus amino acids of PAX8 (aa 2–15) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986562 |
Product Specific Information
- Predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this family typically encode proteins containing a paired box domain, an octapeptide, and a paired-type homeodomain.
This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes.
Mutations in this gene are associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical follicular thyroid adenomas.
Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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