Thermo Fisher Scientific TrxR1 Polyclonal Antibody
TrxR1 단백질을 인식하는 Goat Polyclonal 항체로, Western blot과 IHC(Paraffin) 실험에 적합합니다. Human에 반응하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 보관하며, -20°C에서 냉동 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (TKRSGASILQAGC) corresponding to the C-terminus amino acids of TXNRD1 (aa 635–648) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10987187 |
Product Specific Information
- This antibody is predicted to react with porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer using FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes has a common stem-loop structure, the SECIS element, necessary for recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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