Thermo Scientific™

BM(PEG)2 (1,8-bismaleimido-diethyleneglycol)

Thermo Scientific Pierce BM(PEG)2 is a bismaleimide-activated PEG compound for crosslinking between sulfhydryl (—SH) groups in proteins and other thiol자세히 알아보기

Thermo Scientific Pierce BM(PEG)2 is a bismaleimide-activated PEG compound for crosslinking between sulfhydryl (—SH) groups in proteins and other thiol molecules. The maleimide groups at either end of the PEG2 spacer react specifically and efficiently with reduced sulfhydryls at pH 6.5-7.5 to form stable thioether bonds.

Features of BM(PEG)2:

• Reactive groups: maleimide (both ends)
• Reactive towards: sulfhydryl groups
• Long, pegylated, sulfhydryl-to-sulfhydryl crosslinkers, composed of maleimide groups and 2-unit polyethylene glycol spacer arm
• PEG spacers provide unique advantages, including enhanced solubility, increased stability, reduced tendency toward aggregation and reduced immunogenicity
• Pure compounds with defined structure and molecular weight, ensuring reproducible protein-modification effects
• Ideal for small molecule or peptide conjugations

Alternative Names for BM(PEG)n:

• Bismaleimide-dPEG
• Mal-PEG-Mal
• BM(PEO)2
• BM-PEO3

Product References:

Crosslinker Application Guide -- search for recent literature references for this product

Related Products
BMB (1,4-bismaleimidobutane)
BMH (bismaleimidohexane)
BMOE (bismaleimidoethane)
BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)

사양

화학물질 반응성Sulfhydryl-Sulfhydryl

CleavableNo

설명BM(PEG)2

분자량308.29

페길레이티드Yes

스페이서 암 길이14.7 Å

세포 투과성No

배송 조건Ambient

제품라인Pierce™

라벨링 방법Chemical Labeling

교차결합제 유형Homobifunctional

반응성 부분Maleimide

스페이서Medium (10 to 30 Å)

형태Solid

수량50 mg

용해도Water

형식Standard

수용성Yes

제품 유형Crosslinker

Unit SizeEach