Thermo Scientific™

SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))

Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a자세히 알아보기

Thermo Scientific Pierce SMPH is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a long spacer arm (14.2 angstroms).

Features of SMPH:

• Reactive groups: NHS ester and maleimide
• Reactive towards: amino and sulfhydryl groups
• Slightly longer and more soluble than SMPB
• NHS ester reacts with primary amines at pH 7-9, forming a stable amide bond
• Maleimide reacts with -SH groups at pH 6.5-7.5, forming a stable thioether bond
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
SMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))

사양

화학물질 반응성Amine-Sulfhydryl

CleavableNo

설명SMPH

분자량379.36

페길레이티드No

스페이서 암 길이14.2 Å

세포 투과성Yes

배송 조건Ambient

제품라인Pierce™

라벨링 방법Chemical Labeling

교차결합제 유형Heterobifunctional

반응성 부분Maleimide, NHS Ester

스페이서Medium (10 to 30 Å)

형태Solid

수량50 mg

용해도DMF, DMSO

형식Standard

수용성No

제품 유형Crosslinker

Unit SizeEach