Thermo Scientific™

DTME (dithiobismaleimidoethane)

Thermo Scientific Pierce DTME is a mid-length, maleimide crosslinker for reversible covalent conjugation between sulfhydryl groups (e.g., protein or peptide자세히 알아보기

Thermo Scientific Pierce DTME is a mid-length, maleimide crosslinker for reversible covalent conjugation between sulfhydryl groups (e.g., protein or peptide cysteines) by reduction of the disulfide bond in the center of the spacer arm.

Features of DTME:

• Reactive groups: maleimide (both ends)
• Reactive towards: sulfhydryl groups
• Long (13.3A), cleavable, sulfhydryl-to-sulfhydryl crosslinker, composed of maleimide groups and 11-atom disulfide spacer arm
• Water-insoluble—dissolve first in DMF or DMSO, then add to aqueous reaction buffers
• Cleavable by reduction of disulfide spacer arm with DTT, TCEP or other reducing agent

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
BMH (bismaleimidohexane)

사양

화학물질 반응성Sulfhydryl-Sulfhydryl

CleavableBy Thiols

설명DTME

분자량312.36

페길레이티드No

스페이서 암 길이13.3 Å

세포 투과성Yes

배송 조건Ambient

제품라인Pierce™

라벨링 방법Chemical Labeling

교차결합제 유형Homobifunctional

반응성 부분Maleimide

스페이서Medium (10 to 30 Å)

형태Solid

수량50 mg

용해도DMF, DMSO

형식Standard

수용성No

제품 유형Crosslinker

Unit SizeEach