Thermo Fisher Scientific TGF beta 2 Propeptide Polyclonal Antibody
TGF beta 2 전구체를 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Protein A로 정제된 액상 형태입니다. -20°C 보관, 연구용 전용입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:300 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TGF-beta 2 (amino acids 154–197) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transforming Growth Factor (TGF) betas mediate many cell-to-cell interactions during embryonic development. Three TGF betas (TGF beta 1, TGF beta 2, TGF beta 3) have been identified in mammals. Each is synthesized as a precursor protein cleaved to yield a 112-amino-acid polypeptide associated with the latent portion of the molecule.
TGF betas are multifunctional, influencing cell proliferation, differentiation, and other cellular processes across various cell types. Both transformed and nonneoplastic tissues release TGF, and most mammalian cells possess specific TGF receptors.
TGF beta exhibits dual roles—stimulating or inhibiting cell proliferation depending on cell type. Generally, mesenchymal cells are stimulated, while epithelial or neuroectodermal cells are inhibited.
TGF beta 2 is produced by many cell types, found abundantly in porcine platelets and mammalian bone, and is the predominant isoform in body fluids such as amniotic fluid, breast milk, and ocular humors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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