Thermo Fisher Scientific SNAIL Polyclonal Antibody
SNAIL 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 종양 침윤 및 EMT 연구에 적합.
- 카탈로그번호
- PA5119629
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SNAIL Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human SNAIL (aa 1–49) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913202 |
Product Specific Information
- Positive Control: Human kidney tissue, SiHa, K562, HUVEC, LOVO, human tonsil tissue, human liver cancer tissue, mouse testis tissue
- Subcellular Location: Nucleus, Cytoplasm
Target Information
Zinc finger protein SNAI1 (SNAIL) is a zinc finger transcriptional repressor that downregulates ectodermal gene expression within the mesoderm, contributing to mesoderm and neural crest formation. SNAI1 plays a key role in tumor invasion through E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, SNAI1 and/or SNAI2 (Slug) expression are linked to E-cadherin repression, metastasis, recurrence, and poor prognosis. Snail 1 protein in the stroma may serve as a putative prognostic marker for colon tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.