Thermo Fisher Scientific RPA4 Polyclonal Antibody
RPA4 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot에 적합하며 인간, 마우스, 랫트에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, DNA 복제 및 수선 연구에 유용합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human RPA4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719466 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% (by SDS-PAGE).
Target Information
Single-stranded DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, including mitochondria, phages, and viruses.
Replication protein A (RPA) is a highly conserved eukaryotic heterotrimeric SSB composed of three subunits that play key roles in DNA replication, recombination, and repair.
RPA is a major damage-recognition structure involved in the early stages of nucleotide excision repair and may also function in telomere maintenance.
Human RPA (hRPA) binds DNA with molecular polarity, initially attaching to the 5′ side of ssDNA and extending toward the 3′ direction to form a stable complex.
RPA 34 kDa subunit, also known as RPA4 (Replication Factor A Protein 4), contains 261 amino acids, localizes to the nucleus, and is preferentially expressed in colon mucosa and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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