Thermo Fisher Scientific ALDH1A1 Polyclonal Antibody
ALDH1A1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, Flow Cytometry에 사용 가능. 인간에 반응하며, 마우스 및 영장류에서도 예측 반응. 2 mg/mL 농도의 액상 형태로 제공되며, 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 302–331 of human ALDH1A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, Size-exclusion, Dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2273727 |
Product Specific Information
This antibody is predicted to react with mouse and non-human primate based on sequence homology.
Target Information
ALDH1A1 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme in the major oxidative pathway of alcohol metabolism. Two major liver isoforms—cytosolic and mitochondrial—can be distinguished by electrophoretic mobility, kinetic properties, and subcellular localization. Most Caucasians have both isozymes, while approximately 50% of Orientals possess only the cytosolic isozyme, lacking the mitochondrial form. The higher frequency of acute alcohol intoxication among Orientals may be related to the absence of the mitochondrial isozyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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