Thermo Fisher Scientific HLA-ABC Polyclonal Antibody
HLA-ABC 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 및 마우스 반응성. Affinity chromatography로 정제되었으며 1 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HLA-A (Accession P04439), corresponding to amino acid residues R106–S156 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899999 |
Product Specific Information
This antibody detects endogenous levels of total HLA Class I.
Target Information
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin.
They carry foreign determinants important for immune recognition by cytotoxic T cells, playing a key role in antiviral and antitumor defense.
Human HLA-class I antigens are represented by HLA-A, HLA-B, and HLA-C molecules.
HLA and MHC antibodies are essential in Immunopeptidomics research, aiding in the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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