Thermo Fisher Scientific HLA-G (soluble) Monoclonal Antibody (5A6G7), Biotin
인간 HLA-G5 및 HLA-G6 분비형 단백질을 특이적으로 인식하는 단클론 항체로, Biotin으로 표지되어 다양한 면역분석에 활용 가능. Western blot, IHC, Flow cytometry 등 다중 응용에 적합하며, HLA-G1과 교차반응하지 않아 isoform 구분에 유용. 연구용으로만 사용.
- 카탈로그번호
- MA110360
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HLA-G (soluble) Monoclonal Antibody (5A6G7), Biotin
Thermo Fisher Scientific HLA-G (soluble) Monoclonal Antibody (5A6G7), Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1–4 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A6G7 |
| Immunogen | C-terminal amino acid sequence (22-mer) of soluble HLA-G5 and HLA-G6 proteins coupled to ovalbumin |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151937 |
Product Specific Information
This antibody was generated to a peptide corresponding to the C-intron 4-encoded sequence. It does not cross-react with the full-length HLA-G1 isoform and thus allows distinction between secreted HLA-G5 and HLA-G6 isoforms from shedded HLA-G1.
Target Information
HLA-G belongs to the HLA class I heavy chain paralogues. It is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain (~45 kDa) is membrane-anchored and encoded by a gene containing 8 exons:
- Exon 1: Leader peptide
- Exons 2–3: α1 and α2 domains (peptide binding)
- Exon 4: α3 domain
- Exon 5: Transmembrane region
- Exon 6: Cytoplasmic tail
HLA-G is expressed on fetal-derived placental cells.
HLA and MHC antibodies play a significant role in immunopeptidomics, enabling identification and characterization of neoantigens via high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.