Thermo Fisher Scientific GLT-1 Polyclonal Antibody
GLT-1 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot과 면역세포화학(ICC/IF)에 사용 가능하며, EAAT2 단백질의 내인성 수준을 검출합니다. 친화 크로마토그래피로 정제된 액상 형태의 항체입니다.
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- PA5115151
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC1A2 (Accession P43004), corresponding to amino acid residues M125–L175 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899787 |
Product Specific Information
This antibody detects endogenous levels of total EAAT2.
Target Information
Excitatory amino acid transporter 2 (EAAT2) is a member of the solute transporter protein family. It is the principal membrane-bound transporter responsible for clearing the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Proper glutamate clearance is essential for normal synaptic activation and to prevent neuronal damage caused by excessive activation of glutamate receptors. Mutations or decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS). Alternatively spliced transcript variants of this gene have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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