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Thermo Fisher Scientific CD335 (NKp46) Monoclonal Antibody (29A1.4), FITC, eBioscience
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Thermo Fisher Scientific CD335 (NKp46) Monoclonal Antibody (29A1.4), FITC, eBioscience

상품 한눈에 보기

마우스 NKp46(CD335)을 인식하는 단클론 항체로, FITC로 표지되어 있습니다. Flow cytometry에 최적화되어 있으며 NK 세포 표지 및 활성화 연구에 적합합니다. 0.5 mg/mL 농도의 액상 형태로 제공되며 4°C, 암조건에서 보관합니다.

카탈로그번호
11-3351-8x (2개 옵션)
판매단위
pk
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2개 옵션
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마지막 업데이트 2025. 08. 04. 오후 07:09
Thermo Fisher Scientific 11-3351-82 CD335 (NKp46) Monoclonal Antibody (29A1.4), FITC, eBioscience 100 ug pk판매 단위 pk ·
재고 확인 필요
409,600원VAT 포함 450,560원
Thermo Fisher Scientific 11-3351-80 CD335 (NKp46) Monoclonal Antibody (29A1.4), FITC, eBioscience 25 ug pk판매 단위 pk ·
재고 확인 필요
181,900원VAT 포함 200,090원

Thermo Fisher Scientific · Thermo Fisher Scientific CD335 (NKp46) Monoclonal Antibody (29A1.4), FITC, eBioscience

Applications and Tested Dilution

Application Tested Dilution Publications
Immunohistochemistry (Paraffin) (IHC (P)) - View 1 publication
Immunohistochemistry (Frozen) (IHC (F)) - View 1 publication
Flow Cytometry (Flow) 1 µg/test View 34 publications

Product Specifications

항목 내용
Species Reactivity Mouse
Published Species Mouse
Host / Isotype Rat / IgG2a, kappa
Recommended Isotype Control Rat IgG2a kappa Isotype Control (eBR2a), FITC, eBioscience™
Class Monoclonal
Type Antibody
Clone 29A1.4
Conjugate FITC
Excitation / Emission Max 498 / 517 nm
Form Liquid
Concentration 0.5 mg/mL
Purification Affinity chromatography
Storage Buffer PBS, pH 7.2
Contains 0.09% sodium azide
Storage Conditions 4°C, store in dark, DO NOT FREEZE
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_1210844

Available Conjugate Formats

  • Alexa Fluor 700
  • APC
  • APC-eFluor 780
  • Biotin
  • Brilliant Violet 711
  • eFluor 450
  • eFluor 660
  • Functional Grade
  • PE
  • PE-Cyanine7
  • PE-eFluor 610
  • PerCP-eFluor 710
  • Super Bright 436
  • Super Bright 600
  • Super Bright 645
  • Request custom conjugation

Product Specific Information

The monoclonal antibody 29A1.4 recognizes mouse NKp46 (CD335), a member of the natural cytotoxicity receptor (NCR) family. CD335 is a glycoprotein with two Ig-like domains and a short cytoplasmic tail, expressed specifically on NK cells, including immature NK cells (DX5⁻ CD3⁻), allowing discrimination between NKT and NK cells (NKp46⁺, CD3⁻).

Unlike many NK markers, staining with 29A1.4 is not strain-specific and has been shown in C57Bl/6, SJL, CBA/CA, and BALB/C strains. NKp46 plays a role in NK cell-mediated lysis of tumor and pathogen-infected cells.

The 29A1.4 antibody can activate NK cells in vitro but does not deplete them in vivo.

Applications Reported: Flow cytometric analysis.
Applications Tested: Tested by flow cytometric analysis of mouse splenocytes at ≤1 µg/test. Optimal titration is recommended.
Excitation: 488 nm
Emission: 520 nm
Laser: Blue Laser
Filtration: 0.2 µm post-manufacturing filtered.


Target Information

NKp46 (CD335, NCR1) is a cytotoxicity-activating receptor contributing to the enhanced tumor cell lysis activity of activated NK cells. It consists of two Ig-like domains and is structurally related to leukocyte immunoglobulin-like (LIR) and killer inhibitory receptors (KIR).


For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.


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