Thermo Fisher Scientific ITGA4 Monoclonal Antibody (44H6)
인간 CD49d(ITGA4)를 검출하는 마우스 모노클로날 항체로, IHC(F) 및 유세포분석(Flow)에 적합합니다. 비결합형 액상 형태이며 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:40 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 44H6 |
| Immunogen | HOON pre-B leukaemia cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_1955346 |
Product Specific Information
MA1-33573 detects CD49d from human samples.
Target Information
Integrin alpha 4 (also known as CD49d and ITGA4) is part of the integrin alpha chain family. Integrins are heterodimeric membrane proteins composed of alpha and beta chains. The alpha4 chain associates with either beta1 or beta7 chain. Ligand-binding sites for both integrin alpha4β1 and alpha4β7 are located on the alpha4 chain, binding ligands such as MadCAM, VCAM, and fibronectin. MadCAM is the principal ligand for integrin alpha4β7. HIV-1 envelope has been shown to mimic MadCAM by binding to and signaling through integrin alpha4β7, the gut mucosal homing receptor for peripheral T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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