Thermo Fisher Scientific CD51/CD61 Monoclonal Antibody (23C6)
CD51/CD61 복합체를 인식하는 Mouse IgG1 단일클론 항체로, Human, Rat, Chicken 시료에 반응합니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능하며, Protein A 정제된 액상 형태로 1 mg/mL 농도입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 1 publication |
| Flow Cytometry (Flow) | 1:40–1:80 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Functional Assay | Assay-dependent | - |
| Immunomicroscopy (IM) | Assay-dependent | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Chicken, Human, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 23C6 |
| Immunogen | Osteoclasts from osteoclastomas |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1955362 |
Product Specific Information
- For flow cytometry, use 10 µL of the suggested working dilution to label 10^6 cells in 100 µL.
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex that binds vitronectin at the RGD sequence.
This complex also binds fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin, and collagen.
Reacts with osteoclasts, placenta, melanoma cell lines, and weakly with platelets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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