Thermo Fisher Scientific alpha-II Spectrin Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-4 µg/mL

-

Immunohistochemistry (IHC)

10-20 µg/ml

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide surrounding amino acid 162 of mouse alpha-Fodrin if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SPTAN1,uniProtId:P16546-1,ncbiNodeId:10090,antigenRange:162,antigenLength:2472,antigenImageFileName:PA1-26484_SPTAN1_P16546-1_Rabbit.svg,antigenImageFileNamePDP:PA1-26484_SPTAN1_P16546-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 30% glycerol, 0.5% BSA, 5mM EDTA

Contains

0.02% sodium azide, 0.03% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2239891

Product Specific Information

PA1-26484 detects alpha Fodrin from human samples.

Target Information

SPTAN1 (spectrin alpha chain, non-erythrocytic 1) is a part of the spectrin family of filamentous cytoskeletal proteins. They function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. SPTAN1 has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.