
Thermo Fisher Scientific SEC23IP Polyclonal Antibody
SEC23IP 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC(P), ICC/IF에 적합합니다. Human, Mouse, Rat에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 단백질 수송 연구 및 세포 내 경로 분석에 활용 가능합니다.
- 카탈로그번호
- PA558378
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEC23IP. Recombinant protein control fragment (Product #RP-97033). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647074 |
Product Specific Information
Immunogen sequence:
HLELKESLSR MGSDLKQGFI SSLKSAWQTL NEFARAHTSS TQLQEELEKV ANQIKEEEEK QVVEAEKVVE SPDFSKDEDY LGKVGML
Antigen sequence identity:
- Mouse: 95%
- Rat: 98%
Target Information
SEC23IP is involved in protein transport from the endoplasmic reticulum to the Golgi apparatus. The protein encoded by this gene was identified by its interaction with a mouse protein similar to yeast Sec23p, an essential component of the COPII complex. This protein shares significant similarity with phospholipid-modifying proteins, especially phosphatidic acid preferring-phospholipase A1. Overexpression of this protein has been shown to cause disorganization of the endoplasmic reticulum-Golgi intermediate compartment and Golgi apparatus, suggesting its role in the early secretory pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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