Thermo Fisher Scientific Nrf2 Recombinant Rabbit Monoclonal Antibody (HL1021)
Nrf2 단백질 검출용 Thermo Fisher Scientific의 재조합 토끼 단일클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간, 생쥐, 랫드 반응성. 고순도 Protein A 정제, 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific Nrf2 Recombinant Rabbit Monoclonal Antibody (HL1021)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL1021 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human NRF2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911512 |
Product Specific Information
- Store as a concentrated solution.
- Centrifuge briefly prior to opening vial.
- For short-term storage (1–2 weeks), store at 4°C.
- For long-term storage, aliquot and store at -20°C or below.
- Avoid multiple freeze-thaw cycles.
Target Information
Nfr1 (also designated TCF11), Nrf2, and Nfr3 are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE (Maf recognition elements) sequences.
Nrf2 is widely expressed and translocates to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from the repressor protein Keap1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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