Thermo Fisher Scientific BIKE Polyclonal Antibody
Human BIKE 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IP에 적합. 고순도(>95%) 항원 친화 정제 제품. 세린/트레오닌 키나아제 연구 및 골형성 관련 신호전달 연구에 활용 가능. 연구용 전용 시약.
- 카탈로그번호
- PA575593
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1000–1:2000
Immunoprecipitation (IP)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human BIKE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2719321 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as confirmed by SDS-PAGE.
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues regulate numerous cellular functions such as division, homeostasis, and apoptosis. Serine/threonine (Ser/Thr) protein kinases are central to these processes.
BMP2K (BMP2 inducible kinase), also known as BIKE, is a 1,161 amino acid nuclear protein containing one kinase domain and belonging to the Ser/Thr protein kinase family. It is thought to be involved in osteoblast differentiation and catalyzes ATP-dependent phosphorylation of bone morphogenic proteins (BMPs), which are essential for cartilage and bone formation. BMP2K may play a role in signaling pathways mediating bone growth and cellular differentiation. Three isoforms of BMP2K exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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