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Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/8591R)
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Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/8591R)

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PD-L1(Programmed Death Ligand 1) 표적을 인식하는 재조합 토끼 단클론 항체. 인체 시료에 반응하며 IHC(P) 실험에 적합. Protein A/G 정제 및 PBS 버퍼 내 0.05% BSA 함유. 암 면역치료 연구용으로 T세포 반응 조절 연구에 활용 가능.

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Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Recombinant Rabbit Monoclonal Antibody (PDL1/8591R)

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

  • Tested Dilution: 1–2 µg/mL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG, kappa
Expression System HEK293 cells
Class Recombinant Monoclonal
Type Antibody
Clone PDL1/8591R
Immunogen Recombinant fragment (around aa190–290) of human CD274 protein
Conjugate Unconjugated
Form Liquid
Concentration 200 µg/mL
Purification Protein A/G
Storage Buffer PBS with 0.05% BSA
Contains 0.05% sodium azide
Storage Conditions 4°C
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Positive Control: Human placenta, spleen, or tonsil tissue
  • Cellular Location: Cell surface and cytoplasm

Target Information

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. Its receptor, PD-1, negatively regulates T-cell receptor (TCR) signaling. Upon binding to PD-1, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated by IFN-gamma stimulation. PD-L1 plays a critical role in tumor immune evasion mechanisms.


For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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