Thermo Fisher Scientific DGKB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 544-773 of human DGKB (NP_663733.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DGKB,uniProtId:Q9Y6T7-1,ncbiNodeId:9606,antigenRange:544-773,antigenLength:804,antigenImageFileName:PA5-109630_DGKB_Q9Y6T7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109630_DGKB_Q9Y6T7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.2 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855041

Product Specific Information

Immunogen sequence: LMKILKDIEN STEIMLDRWK FEVIPNDKDE KGDPVPYSII NNYFSIGVDA SIAHRFHIMR EKHPEKFNSR MKNKFWYFEF GTSETFSATC KKLHESVEIE CDGVQIDLIN ISLEGIAILN IPSMHGGSNL WGESKKRRSH RRIEKKGSDK RTTVTDAKEL KFASQDLSDQ LLEVVGLEGA MEMGQIYTGL KSAGRRLAQC SCVVIRTSKS LPMQIDGEPW MQTPCTVSTE

Target Information

Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.