Thermo Fisher Scientific ABHD3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total ABHD3.

Target Information

The α/β hydrolase superfamily comprises diverse members involved in important biochemical processes and related diseases. Despite having unrelated sequences and various substrates, they share the canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad composed of histidine, acid, and nucleophile.

Members of this family are often drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders. The ABHD gene subfamily consists of 15 mostly uncharacterized members, most of which utilize a serine nucleophile forming the G-X-S-X-G nucleophile elbow.

• ABHD1: Metabolizes smoking xenobiotics
• ABHD2: Participates in atherosclerosis development
• ABHD3: 409 amino acid single-pass type II membrane protein
• ABHD4: Involved in alternative synthesis of N-acyl ethanolamine (NAE)
• ABHD5: Mutations contribute to Chanarin-Dorfman syndrome
• ABDH6: May play a role in nervous system metabolism and signaling

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일: PA5-103555_ABHD3_Q8WU67-1_Rabbit_PDP.jpeg, PA5-103555_ABHD3_Q8WU67-1_Rabbit.svg)