Thermo Fisher Scientific ABHD13 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

This antibody detects endogenous levels of total ABHD13.

Target Information

The α/β hydrolase superfamily comprises diverse members involved in important biochemical processes and associated with various diseases. Despite having unrelated sequences and different catalytic activities, they share the canonical α/β hydrolase fold composed of an eight-stranded parallel α/β structure and a catalytic triad (histidine, acid, nucleophile).

Members of this superfamily are often drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and clotting disorders. The ABHD gene subfamily includes 15 members, most of which utilize a serine nucleophile forming the G-X-S-X-G nucleophile elbow.

• ABHD1: Involved in metabolizing smoking xenobiotics
• ABHD2: Participates in atherosclerosis development
• ABHD4: Functions in an alternative synthesis pathway of NAE
• ABHD5: Mutations cause Chanarin-Dorfman syndrome
• ABHD6: May play a role in nervous system metabolism and signaling
• ABHD13: A 337 amino acid single-pass membrane protein belonging to the ABHD family

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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