Thermo Fisher Scientific ITK Polyclonal Antibody
ITK 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC, Flow cytometry에 사용 가능. 염소 유래 IgG 항체이며, T세포 관련 연구에 적합. 0.5 mg/mL 농도의 액상 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 3.75 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KERPEDRPAFSR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933046 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
ITK (IL2-inducible T-cell kinase) is a tyrosine kinase expressed in T-cells containing both SH2 and SH3 domains. It plays a role in T-cell proliferation and differentiation.
The Tec family of non-receptor tyrosine kinases includes Tec, Itk (also known as Emt or Tsk), Btk (Atk, BPK, or Emb), Bmx, Txk (Rlk), and Dsrc28C.
All members contain SH3 and SH2 domains, and except Txk and Dsrc28C, also contain PH and TH domains in their amino termini.
Itk associates with CD28 and becomes activated subsequent to CD28 ligation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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