Thermo Fisher Scientific MMP10 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MMP10. Validated for WB and IHC(P) applications. Antigen affinity purified, supplied as liquid at 1 mg/mL. Recommended controls include HepG2 and MMP10-transfected 293T. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:10,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–261 of Human MMP10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547220 |
Product Specific Information
- Recommended positive controls: HepG2, human MMP10-transfected 293T, HepG2 conditioned medium
- Predicted reactivity: Mouse (83%), Rat (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MMP10 (matrix metalloproteinase 10) is a member of the matrix metalloproteinase family, generally secreted in its pro form and further modified by extracellular proteinases. It requires zinc and calcium as cofactors for enzymatic activity. MMP10 is involved in activation of pro-collagenase, collagen catabolism, fibronectin degradation, and tissue remodeling. In humans, the MMP10 gene is located on chromosome 11.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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