Thermo Fisher Scientific PAX5/BSAP (Early B-Cell Marker) Monoclonal Antibody (PCRP-PAX5-1B7)
PAX5/BSAP 단백질을 인식하는 마우스 단일클론 항체로, B세포 초기 분화 마커 분석에 적합합니다. Western blot, IHC, IP 등 다양한 응용에 사용 가능하며, 고순도 Protein A/G 정제 및 보존제 무첨가 PBS 용액 형태로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunoprecipitation (IP) | 2–4 µg/mg |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-PAX5-1B7 |
| Immunogen | Recombinant full-length human PAX5 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PAX5 is a member of the paired box (PAX) family of transcription factors. These proteins are key regulators in early development, and alterations in their expression are associated with neoplastic transformation.
PAX5, also known as B-cell lineage-specific activator protein (BSAP), is expressed at early but not late stages of B-cell differentiation. Expression has also been detected in developing CNS and testis, suggesting roles in neural development and spermatogenesis.
Mutations in the PAX5 gene can result in leukemia, particularly acute lymphoblastic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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