Thermo Fisher Scientific RBM28 Polyclonal Antibody
Thermo Fisher Scientific의 RBM28 폴리클로날 항체는 인간 RBM28 단백질에 특이적이며, Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제된 비접합 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
- 카탈로그번호
- PA553909
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RBM28. Recombinant protein control fragment (Product #RP-92674). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646380 |
Product Specific Information
Immunogen sequence:
RKLLLSATSG EKGVRIKECR VMRDLKGVHG NMKGQSLGYA FAEFQEHEHA LKALRLINNN PEIFGPLKRP IVEFSLEDRR KLKMKELRIQ RSLQKMRSKP ATGEPQKGQP EPAKDQQQK
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 82%
Target Information
Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes. Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With VAPA, may regulate ER morphology. Has a role in regulation of the actin cytoskeleton, cell polarity, and cell adhesion. Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3. Also binds 25-hydroxycholesterol and cholesterol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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