Thermo Fisher Scientific CROT Polyclonal Antibody
Thermo Fisher Scientific의 CROT Polyclonal Antibody는 인간 CROT 단백질을 인식하는 토끼 다클론 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS, 40% 글리세롤, 0.02% 나트륨 아지드 용액에 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CROT. Recombinant protein control fragment (Product # RP-92589) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2640171 |
Product Specific Information
Immunogen sequence:
LAKSTEERTF QYQDSLPSLP VPSLEESLKK YLESVKPFAN QEEYKKTEEI VQKFQSGIGE KLHQKLLERA KGKRNWLEEW WLNVAYLDVR IPSQLNVNFA GPAAHFEHYW PPKEGTQLER GSITLWH
Sequence identity (orthologs):
- Mouse: 87%
- Rat: 89%
Target Information
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long-chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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