Thermo Fisher Scientific Influenza A PB2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:10,000
• View 2 publications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:1,000
• View references

In vitro Assay (IV)

• Tested Dilution: —
• View 1 publication

Product Specifications

Product Specific Information

• Recommended positive controls: Influenza virus (A/WSN/1933(H1N1))-infected DF-1 cell lysates
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Influenza A virus contains eight single-stranded, negative-sense RNAs. Each RNA is associated with viral RNA-dependent RNA polymerase, which consists of PA, PB1, and PB2 proteins.
PB1 is the catalytic subunit responsible for nucleotide polymerization and transcription initiation. PB1 and PB2 can be crosslinked to synthetic RNA with the 3′ terminal sequence of viral RNA.
PB1 and PB2 may also be involved in recognition of the promoter and/or replication origin on template viral RNA. PB2 is the cap 1-recognition protein that binds to the cap structure of host mRNA, which acts as a primer for transcription to produce viral mRNA.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.