Thermo Fisher Scientific TNFR2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 TNFR2 폴리클로날 항체로 Western Blot 및 IHC(P) 적용 가능. Goat 유래 IgG 형식으로 0.5 mg/mL 농도의 액상 형태. 암모늄 황산염 침전으로 정제되었으며, TBS(pH 7.3) 버퍼에 0.5% BSA 포함. -20°C 보관, 동결/해동 반복 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–0.6 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence KHFCNKTSDTVCAD (aa 65–78) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933430 |
Product Specific Information
- The immunizing peptide represents part of a potential extracellular domain.
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha.
The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
TNFR2 mediates most of the metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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