Thermo Fisher Scientific RPL14/Ribosomal Protein L14 Polyclonal Antibody

Thermo Fisher Scientific RPL14 / Ribosomal Protein L14 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 60S subunit and belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain and is located in the cytoplasm.
This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein.
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes dispersed throughout the genome.
References:

• Aoki M., Diabetes 45:157–164 (1996)
• Tanaka M., Biochem. Biophys. Res. Commun. 243:531–537 (1998)
• Yoshihama M., Genome Res. 12:379–390 (2002)

Usage Note

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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