Thermo Fisher Scientific CD44v4 Monoclonal Antibody (CD44v4, 1219)
CD44v4 단백질을 인식하는 Mouse Monoclonal Antibody로 인간 시료에 반응합니다. IHC(P) 실험에 적합하며, Protein A/G로 정제된 고순도 항체입니다. PBS 버퍼에 보존제가 없으며 -20°C 이하에서 안정적으로 보관 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CD44v4, 1219 |
| Immunogen | Recombinant fragment corresponding to the v4 domain of human CD44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C followed by cooling at room temperature for 20 minutes.
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and by some epithelial cells of the intestine and breast.
Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration.
It participates in various cellular functions including lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in some carcinomas, potentially related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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