Thermo Fisher Scientific MCM3 Monoclonal Antibody (4F7)
Thermo Fisher Scientific의 MCM3 Monoclonal Antibody (4F7)는 인간과 생쥐 시료에 반응하는 고특이성 항체로, Western Blot 및 ELISA에 적합합니다. MCM3 단백질 검출에 사용되며, 액상 형태로 제공되고 -20°C에서 보관 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2a, lambda |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F7 |
| Immunogen | MCM3 (NP_002379, 699–808 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
AKDGDSYDPY DFSDTEEEMP QVHTPKTADS QETKESQKVE LSESRLKAFK VALLDVFREA HAQSIGMNRL TESINRDSEE PFSSVEIQAA LSKMQDDNQV MVSEGIIFLI
Target Information
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication.
The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.
This protein is a subunit of the protein complex that consists of MCM2–7. It has been shown to interact directly with MCM5/CDC46.
This protein also interacts with, and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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