Thermo Fisher Scientific Heparin Cofactor II Recombinant Rabbit Monoclonal Antibody (25)
Recombinant rabbit monoclonal antibody recognizing Mouse SerpinD1/Heparin Cofactor II. Suitable for WB, ELISA, and IP. Offers high specificity, lot-to-lot consistency, and preservative-free formulation for reliable research use.
- 카탈로그번호
- MA529795
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:25,000–1:50,000 |
| Immunoprecipitation (IP) | 0.2–1 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 25 |
| Immunogen | Recombinant Mouse SerpinD1 protein (Met1–Ser478) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785617 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned, and individual clones are screened to select the best candidates. Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the rabbit immune repertoire
This antibody has specificity for Mouse SerpinD1/Heparin Cofactor II.
Target Information
The gene encodes a serine proteinase inhibitor that rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. It contains five exons and four introns and shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations are associated with heparin cofactor II deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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